Product Name :
NQO2 Recombinant Rabbit Monoclonal Antibody [SC06-68]
Predicted band size :
26 kDa
Observed band size :
26 kDa
Synonyms:
DHQV antibody DIA6 antibody EC 1.10.99.2 antibody MGC94180 antibody NAD(P)H dehydrogenase quinone 2 antibody NAD(P)H menadione oxidoreductase 1 dioxin inducible 2 antibody NAD(P)H menadione oxidoreductase 2 dioxin inducible antibody NMOR2 antibody NQO 2 antibody NQO2 antibody 展开
Function :
NAD(P)H dehydrogenase, quinone 2, also known as QR2, is a protein that in humans is encoded by the NQO2 gene. It is a phase II detoxification enzyme which can carry out two or four electron reductions of quinones. Its mechanism of reduction is through a ping-pong mechanism involving its FAD cofactor. Initially in a reductive phase NQO2 binds to reduced dihydronicotinamide riboside (NRH) electron donor, and mediates a hydride transfer from NRH to FAD. Then, in an oxidative phase, NQO2 binds to its quinone substrate and reduces the quinone to a dihydroquinone. Besides the two catalytic FAD, NQO2 also has two zinc ions. It is not clear whether the metal has a catalytic role. NQO2 is a homodimer. NQO2 can be inhibited by resveratrol. One of QR2’s binding sites responds to 2-iodomelatonin, and has been referred to as MT3.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human NQO2 aa 2-49 / 231.1H-Pyrazole-4-carbaldehyde supplier
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IHC-P
Coupling :
unconjugated
Clone number:
SC06-68
RRID:
AB_3069979
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.Tetramethylammonium (acetate) site Aliquot store at -20℃ or -80℃.PMID:33645442 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 26 kDa
Positive control :
Hela cell lysates, human kidney tissue.