Product Name :
NF-kB p105/p50 Recombinant Rabbit Monoclonal Antibody [SZ20-01]
Predicted band size :
105/50 kDa
Observed band size :
105/50 kDa
Synonyms:
DKFZp686C01211 antibody DNA binding factor KBF1 antibody DNA binding factor KBF1 EBP1 antibody DNA-binding factor KBF1 antibody EBP 1 antibody EBP-1 antibody EBP1 antibody KBF1 antibody MGC54151 antibody NF kappa B antibody 展开
Function :
Proteins encoded by the v-Rel viral oncogene and its cellular homolog, c-Rel, are members of a family of transcription factors that include the two subunits of the transcription factor NFkB (p50 and p65) and the Drosophila maternal morphagen, dorsal. These proteins share sequence homology over a region of 300 amino acids at their NH2-terminus, the region that contains their DNA binding and dimerization domains. The DNA binding activity of NF B is activated and rapidly transported from the cytoplasm to the nucleus in cells exposed to mitogens or growth factors.1427158-38-0 Price cDNAs encoding precursors for two distinct proteins have been described. These proteins, designated p105 and p100, are highly related but map on different chromosomes. The p105 (p110) precursor contains p50 at its N-terminus and a C-terminal region that when expressed as a separate molecule, designated PdI, binds to p50 and regulates its activity.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within human NFkB p105/p50 aa 330-370.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IHC-P, ICC, FC, IF-Tissue
Coupling :
unconjugated
Clone number:
SZ20-01
RRID:
AB_3065033
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.PdCl2(dtbpf) site Aliquot store at -20℃ or -80℃.PMID:33610508 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 105/50 kDa
Positive control :
THP-1 cell lysate, Raji cell lysate, Daudi cell lysate, MCF7 cell lysate, NIH/3T3 cell lysate, Hela cell lysate, PC-12 cell lysate, human tonsil tissue, human spleen tissue, mouse bladder tissue, mouse prostate tissue.